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With any compound that goes into your body there is the possibility of side effects. In the case of LGD 4033 Ligandrol, they are very few and usually only occur while your body gets used to the substance. The two main side effects that may occur are dry mouth and headaches. If this seems to get worse over time, it is recommended to speak with a doctor. 

Although LGD 4033 has been accepted throughout the bodybuilding community as a way to gain muscle, its original intent was to be used as a treatment for muscle wasting and osteoporosis. Ligand Pharmaceuticals were the founders of LGD 4033 and saw its potential to stimulate muscle growth for the users of this SARM. The benefit of using LGD 4033 over anabolic steroids is that you avoid some of the highly negative effects that comes with the use of steroids.

As it was mentioned above, SARMs work by selectively connecting to androgen receptors in both bone and muscle tissue, the same is true for LDG 4033. Because of this selectivity, you can avoid it connecting with your vital organ tissues and causing further problems such as those associated with anabolic steroids.

Animal and Human Studies with LGD 4033 Ligandrol

Since becoming a patented product back in 2009, LGD 4033 has undergone several studies. One of the first studies done with humans had its finding published back in 2010. However, most of these trials done with LGD 4033 have been done with animal species such as mice, rats, and horses.

In one of the studies completed by its creators, Ligand Pharmaceuticals, Ligandrol was tested to see its effects on osteopenic female rats. For this particular study, a twelve week time frame was carved out to assess the effects. The doses of LGD 4033 were varied throughout the study with rats receiving at minimum a dose of 0.03mg/kg and at most 0.3mg/kg per day. Throughout the course of the study and at the conclusion it was found that those female rats that were treated with Ligandrol had an increase in both the bending strength of their bones as well as the bone density.

A study done with humans that was published in 2010, 76 healthy men were subject to various dosages of LGD 4033. The men were first divided into four groups with one group as the placebo. This particular group did not receive the LGD 4033 treatment. The remaining three groups were either administered 0.1mg, 0.3mg or 1.0mg depending on which group they were respectively assigned to. The study ran a total of twenty one days and once this twenty one day period was completed it was surmised that LGD 4033 was well tolerated by the test subjects. In addition to this information it was also deduced that even with LGD 4033 taken over a shorter period of time, participants saw an increase in lean muscle mass.

Pros and Cons of Using LGD 4033 for Bodybuilding

Several benefits exist for the use of LGD 4033 Ligandrol for bodybuilding and fitness and they even outweigh the potential side effects that you may experience. The pros of using Ligandrol include things like increased muscle mass, no anabolic steroid side effects, a strengthened musculoskeletal system, improved stamina, and an increase in libido.

 *Disclaimer: These products are not intended to diagnose, treat, or cure any condition or disease. It is not intended for human consumption and is for research purposes only. 

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