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4-Andro is another synthetic non-methylated prohormone but with a distinct metabolic fate that makes it complementary to 1-Andro. Recall that 1-Andro does not convert to estrogen or DHT. While that is certainly a benefit, it also means you need to take something else to help balance the ratio of steroid hormones in the body.

This is precisely why 4-Andro is a perfect adjunct to 1-Andro. 4-Andro is initially converted to 4-androstenediol and then testosterone, in a somewhat similar fashion as 5-DHEA. However, 4-Andro is suggested to be better for muscle gains, and strength building than 5-DHEA since the conversion from 4-androstenediol to testosterone happens at a greater rate.

As such, 4-Andro can be converted into small amounts of estrogen and DHT, thereby helping balance the effects of 1-Andro.

In other words, the anabolic properties of 4-Andro kick in quicker than they do from normal DHEA supplements.

Increasing testosterone levels is well-known to provide a myriad of benefits, including:

  • Increased libido/sex drive
  • Greater muscle gains and intensified pumps during training
  • Enhanced erectile quality
  • Improvement in energy levels and concentration
  • A better sense of vitality, motivation, and confidence
  • Having a more regular appetite
  • Improved sleep quality

Using a prohormone like 4-Andro and/or 1-Andro is generally most beneficial for males over the age of 21 (if not 25 or even 30). Most males produce a normal/adequate amount of testosterone until their mid-late 20s, at which point levels typically start to decline.

Naturally, this has led to sharp increases in diagnoses of males over the age of 30 with low testosterone (clinically known as hypogonadism, andropause, and androgen deficiency).

Common signs and symptoms of low T include:

  • Erectile dysfunction (impotence) and infertility
  • Low libido
  • Loss of muscle mass and strength
  • Feeling lethargic and fatigued despite sleeping a lot
  • Depression and anxiety
  • Poor concentration (brain fog)
  • Small or shrinking testes
  • Loss of body and pubic hair
  • Low red blood cell count (anemia)
  • Brittle bones and malaise
  • Unexpected body fat gain
  • Sleep apnea (or other sleep disorders)
  • Development of breast tissue (gynecomastia)

It’s imperative that you get appropriate blood work done rather than just assuming you have low T based on your symptoms, especially if you’re considering using 1-Andro and/or 4-Andro.

 *Disclaimer: These products are not intended to diagnose, treat, or cure any condition or disease. It is not intended for human consumption and is for research purposes only. 

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